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Current Style: Standard
The Centre for Bioinformatics in Pondicherry University was started as Sub Distributed Information Centre of the Department of Biotechnology, Govt. of India (DBT) in 1991. The mandate of the Centre is to train manpower and conduct research in various areas of Bioinformatics and Computational Biology. Recognizing the progress made by the Centre, DBT upgraded the Centre to a full Centre level in 2002 and several new positions were sanctioned and additional funding was allocated.
The Centre is identified as a Centre of Excellence for Research and Training in the field of Bioinformatics by the Department of Information Technology, Govt. of India, New Delhi from 2007 to 2013 and awarded a special grant of ` 3.69 crores. The Centre has taken up several research projects and has offered modular courses in Bioinformatics under this Grant.
The Centre started a M.Sc., program in Bioinformatics in 2007 supported by the University Grants Commission (UGC) under the scheme of “Innovative Programme - Teaching & Research in Interdisciplinary and Emerging Areas”. For advanced research in Bioinformatics and Computational Biology, the Centre started Ph.D. Programme in 2009. The Centre also received UGC Special Assistance Program (SAP) at the DRS-I level in 2012.The Centre for Bioinformatics has received a grant of ` 1 crore under DST-FIST program for procuring sophisticated equipment.
The Centre started an innovative M.Sc. program in Computational Biology fully funded by DBT in a network mode with Madurai Kamaraj University, Madurai and Anna University, Chennai in 2010. This programme is first of its kind in the country and upgraded to M.Tech program in Computational Biology from 2014 in collaboration with Anna University, Chennai. The Centre has also signed an MoU with Institute of Bioinformatics (IoB), Bangalore for collaborative research and Ph.D. guidance. The Ph.D. students can visit these labs for collaborative research and the details are available at www.bicpu.edu.in.
All students, research scholars and faculty are provided round-the-clock computing facility. The Centre has established a separate wet lab facility with sophisticated equipments. Most of the past students have been placed in various leading research institutions and industries.
Over the past few years, the Centre has taken up research activities in the areas of molecular evolution, systems biology, molecular modeling, structural biology, database development etc., and several papers have been published in highly reputed International and National Journals. The faculty and students have received projects/fellowships from various funding agencies like Department of Biotechnology, Department of Information Technology, University Grants Commission, Council of Scientific and Industrial Research-JRF/SRF, Department of Science and Technology, Bioinformatics National Certificate (BINC), DST-Innovation in Science pursuit for Inspired Research (INSPIRE) and Rajiv Gandhi Fellowship.
The University has provided a new state-of-the art building for our Centre.
Ph.D.
Selection is based on an entrance examination conducted at various Centres by Pondicherry University. The test consists of multiple choice questions in Bioinformatics, Computational Biology, Biochemistry, Molecular Biology, Biotechnology, Chemistry, Biophysics, Computer Science, Statistics and Mathematics at PG level. Candidates who have qualified for JRF (UGC / CSIR-NET / DBT-BINC) are exempted from entrance exam. They can apply directly.
M.Sc. Bioinformatics
Selection is based on an entrance examination conducted at various Centres by Pondicherry University. The test consists of multiple choice questions in Biology, Biochemistry, Molecular Biology, Biotechnology, Chemistry, Biophysics, Computer Science, Statistics and Mathematics.
M.Tech. Computational Biology
Selection will be based on a common entrance examination to be conducted at various Centres by Pondicherry University. The details will be advertised in newspapers and will be available at www.pondiuni.edu.in, www.bicpu.edu.in and www.annauniv.edu. The test consists of multiple choice questions in Biology, Biochemistry, Molecular Biology, Biotechnology, Chemistry, Biophysics, Computer Science, Statistics and Mathematics.
A stipend of ` 8,000/- p.m. will be provided by the Department of Biotechnology, Government of India, New Delhi for all the students admitted.
Special Grants
Some of the Institutions/ Industries who have recruited our students are as follows:
Industry Placements: HCL Info Systems; Tata Consultancy Services; Molecular Connections, Bangalore; Institute of Bioinformatics, Bangalore; Protein Lounge, Bhubaneswar; Genemines, Chennai; BIOBASE Databases Indian Pvt. Ltd., Bangalore; Computational Research Lab, Pune; Jubilant Biosys, Bangalore; Wipro Technologies, Chennai; Schrödinger, Hyderabad; EnZene Biosciences Pvt. Ltd., Bangalore; ABLE C Drive, Bangalore; Persistent Systems Limited, Pune
Teaching/ Research Placements: Pusan National University, South Korea; Stony Brook University, New York; Sungkyunkwan University, South Korea; University of Madras, Chennai; Central Sericulture Research & Training Institute, Mysore; Institute of Microbial Technology Institute, Chandigarh; Centre for Cellular and Molecular Biology, Hyderabad; Alagappa University, Karaikudi; Indian Institute of Technology, Chennai; Jawaharlal Nehru University, New Delhi; National Institute of Immunology, New Delhi; Kumaun University, Nainital; Maulana Azad National Institute of Technology, Bhopal; Amity University; Yeungnam University, South Korea; Maharshi Dayanand University, Haryana; Technical University of Munich, Germany; La Trobe University, Australia; Swinburne University of Technology, Australia; Louisiana State University, USA; University of Illinois; University of Lisbon, Portugal
Infrastructure Facilities – Computers, Networks & Accessories
Servers
Tesla Software Server(4TF) - 1No.: One Super Micro Tesla Server with 2 x Intel Xeon Quad-Core processor @2.4GHz/12MB L3 Cache, 896 GPU based cores (2 x NVIDIA Tesla C2050), 64 GB of DDR3 memory, 6 TB of storage controlled by 128MB cache SAS RAID, 24” wide LED Display and loaded with CentOS.
Web Server, File Server, DB Server, DBT Web Server - 4Nos.: Super Micro HCL Server with 2 x Intel Xeon Quad-Core processor @1.6GHz, 4 GB of DDR2 memory, 6 x 146 GB of storage controlled by SAS RAID, 19”wide LCD Display, Integrated KVM 15” LCD switch and loaded with RHEL 5.
Cluster Server - 3Nos.: HCL Servers with 2 x Intel Xeon @3.2GHz, 4 GB of DDR2 memory, 6 x 146GB of storage controlled by SAS RAID, 17” LCD Display, KVM switch and loaded with RHL Advanced Sever 4.
Mail Server - 1Nos. HCL Server with 2 x Itanium 2@1.7GHz, 4 GB of DDR2 memory, 6 x 146GB of storage controlled by SAS RAID, 17” LCD Display with KVM switch and loaded with RHL Advanced Sever 4.
Domain Name Server - 1Nos.: Wipro Server with Intel Xeon @3.0GHz, 1 GB of memory, 120GB of storage, 17” LCD Display and loaded with RHL Advanced Sever 4.
Domain Controller Server - 1Nos.: HCL AMD Server with AMD 8131/8111 Motherboard, 1 GB of memory, 100GB of storage, 12/24GB-DAT drive, 17” LCD Display and loaded with Windows 2003 Server R2.
Specialized Workstations
Desktop Computers
Network Hardware
Other Facilities
UPS Backup
Infrastructure Facilities – Scientific Software
Molecular Modeling:
Modeler (DISCOVERY STUDIO 2.5), Protein Families (DISCOVERY STUDIO 2.5), Protein Health (DISCOVERY STUDIO 2.5), Protein Refine (DISCOVERY STUDIO 2.5)
Molecular Docking:
Flexible Docking (DISCOVERY STUDIO 2.5), LibDock (DISCOVERY STUDIO 2.5), Ludi (DISCOVERY STUDIO 2.5), LigPrep (DISCOVERY STUDIO 1.5), LigandFIT (DISCOVERY STUDIO 1.5), LigandScore (DISCOVERY STUDIO 1.5), GOLD, AUTODOCK, Database of 1.5million Compound Library (DISCOVERY STUDIO 1.5)
Toxicity Prediction:
ADMET (DISCOVERY STUDIO 2.5), TOPKAT (DISCOVERY STUDIO 2.5)
QSAR:
QSARPlus (VLife)
Rapid calculation of 1000+ descriptors including 2D, 3D alignment independent, atom type count etc.,
GQSAR (VLife)
Intelligent QSAR using molecular fragments of interest and their features, evaluation of descriptors from template scaffold to form relationship with the activity.
Molecular Dynamics:
AMBER 11, GROMOS96
Infrastructure Facilities – Wetlab
Our wet lab is equipped with state of the Art facility, highly sophisticated Akta Purifier for protein purification with various columns (size exclusion, Ion exchange, Affinity). Each and every student is equipped with both Page and slab gel electrophoresis system, which is also equipped with centrifuges, Spectrophotometer and Elisa Reader. We are also having facilities for Protein cloning, expression and purification. We are in the process of furnishing cell culture facilities.
Equipments used for Research:
Equipment used for Teaching:
Infrastructure Facilities – Other Resourses
Resources & Services
Databases Developed
Books
550 books (In addition to the books available in the Central Library)
Journals
Scientific American, Cell, Current Science.
Molecular Evolution, Systems Biology, DNA-Protein Interactions, Comparative Genomics, Protein Structure Modeling, Molecular modeling, X-ray Crystallography, Drug Design, Cell Signaling, Single particle analysis, Medicinal Chemistry, Computational Biology, Molecular Biology.